In the early 1900s Wagner von Jauregg treated syphilis patients with malaria (winning the Nobel Prize). The patients developed malaria, causing a severe fever and killed the syphilis bacteria. Then given the malaria drug quinine and cured. This was used until the development of penicillin.
4 Times the Weather Was Frightening on Halloween

The weather enjoys causing mischief on Halloween. Even though this day isn’t typically a traveling holiday in the United States, the weather can still determine whether it’s a fun night of costumes and sweets or a rainy mess that can ruin weeks of excitement and preparation. Thankfully, Halloween 2016 looks spectacular across most of the United States. As of Friday October 28, the forecast for October 31 anticipates a familiar scenario these days—a ridge of high pressure will blanket most of the country with calm and warmer-than-normal temperatures, with wet weather creeping through the Upper Midwest and northern Rocky Mountains. The Northeast will be chilly for trick-or-treaters, but it pales in comparison to the spooky weather that can plague people celebrating this fun day. Here’s a look at some not-too-thrilling storms that made for scary times in years past.
1. THE PERFECT STORM, 1991
Few storms have reached the legendary status of the Perfect Storm, a ghoulish nor’easter/hurricane hybrid that meandered off the East Coast of the United States for a few days around Halloween in 1991. The storm began as a nor’easter—a strong type of low-pressure system named for the powerful northeasterly winds they bring to the coast—off the Canadian Maritimes, collecting its strength both from strong upper-level winds and by absorbing the remnants of Hurricane Grace. The nor’easter briefly developed into an unnamed hurricane, adding to both its intensity and unusual nature.
Forecasters at the time said that the storm formed in “perfect” conditions (hence its nickname) to cause headaches up and down the coast. The storm’s strong winds generated enormous waves and caused destructive coastal flooding as far south as North Carolina. The storm produced a 5-foot storm surge in Boston, Massachusetts, and waves there reached the height of a three-story building. Thirteen people died during The Perfect Storm—six of them perished when a ship named the Andrea Gail encountered rough waves. This tragedy at sea would become the basis for the 1997 book The Perfect Storm and the popular 2000 film of the same name.
2. THE HALLOWEEN BLIZZARD OF 1991
The Perfect Storm wasn’t the only hazard on Halloween in 1991. While that torrent churned over the western Atlantic Ocean, another powerful storm was developing a few thousand miles to the west over the center of the United States. A strong low-pressure system quickly got its act together during the day on Halloween as it raced northeast toward the Great Lakes, dragging bitterly cold air south from Canada while pumping tropical moisture north from the Gulf of Mexico.
This combination of high moisture and freezing air led to copious amounts of snow in the Upper Midwest, falling so hard and so fast that many folks couldn’t go out trick-or-treating that night. By the time the skies cleared out a day or two later, residents found their towns buried under historic amounts of snow. The airport that serves Minneapolis and St. Paul, Minnesota, measured 28.4 inches of snow by the end of the storm, an all-time record for one snowstorm that still stands today. In the far northeastern corner of the state, Duluth, Minnesota, recorded just over three feet of snow—36.9 inches—making it the highest snowfall total ever recorded in one storm in the entire state of Minnesota.
3. THE HALLOWEEN NOR’EASTER, 2011
October is a rough time to live in the Northeast. Kids growing up on the East Coast are used to having a more volatile Halloween than their counterparts around the rest of the country, as they found out in 2011 when a nor’easter dropped 1 to 2 feet of snow on communities from Virginia to Maine.
It usually doesn’t get cold enough to see much more than flurries in the Mid-Atlantic or lower elevations in the Northeast until after Thanksgiving, but a strong nor’easter barreled its way up the coast just before Halloween and snowed its way into the history books. The cold air that spiraled around the back of the storm tapped into deep tropical moisture to produce a heavy, wet snow across areas that still hadn’t seen all of the leaves fall off the trees. The weight of the leaves and the wet snow easily brought down trees and power lines, knocking out power for several weeks in the hardest-hit areas. The storm reportedly caused more than $3 billion in damages. Many kids in the affected areas couldn’t go trick-or-treating after the storm, forcing many communities to cancel Halloween activities or put them off until crews could clear away the snow and debris.
4. HURRICANE SANDY, 2012
Things got even worse in the Northeast just one year later. One of the worst hurricanes to strike the United States in the past two decades was Hurricane Sandy, an unusual storm that also took advantage of “perfect” conditions in order to turn into a colossal disaster for tens of millions of people.
Hurricane Sandy approached a complicated environment over the Northeast during the last few days of October in 2012. As the category 1 hurricane drew closer to the New Jersey coast, it gradually lost its tropical characteristics as it started to feed its energy from the jet stream above rather than thunderstorms at the center of the storm. Once the hurricane reached shore, it had transitioned into what was essentially the most powerful nor’easter ever recorded. This transition from a large hurricane into an even larger nor’easter raked damaging winds over an area nearly 1000 miles wide at the storm’s largest extent, an immense wind field that pushed a historic and deadly storm surge into the coast.
The evacuations and damage from the storm forced Halloween to the backburner for many coastal communities, but the storm didn’t stop at the coast. During the day on Halloween, the remnants of Hurricane Sandy continued pushing inland, making the evening a cold, dreary, and sometimes snowy mess for the Appalachians and Great Lakes region.
October 30, 2016 – 8:00am
Take Your Pet ‘Camping’ in an Animal-Sized Trailer

If you want to give your indoor pet a taste of outdoor life, Outside reports that Canadian artist/designer Judson Beaumont has designed a line of whimsical, animal-sized trailers.
Modeled after vintage Airstreams and mobile homes, Beaumont’s tiny units come equipped with basic (or not so basic) necessities like stainless steel water and food cups and LED lights. You can even order them in different colors, styles, and sizes, and request customized license plates.
For now, the trailers are only designed for pets up to 20 pounds, and unlike your full-sized camper, they aren’t waterproof. So unless you’re anticipating clear skies, it’s probably best for your pooch to go “camping” in your living room instead of the backyard.
You can view a selection of Beaumont’s trailers below, or visit his website for more information.





All photographs courtesy of Straight Line Designs Inc. // Judson Beaumont.
[h/t Outside]
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October 30, 2016 – 6:00am
Cold Welding Metal in Space (Video)

On the Gemini IV mission, NASA sent out Ed White as the first American astronaut to attempt a spacewalk. After thoroughly enjoying his trip outside the capsule, White returned…but the hatch wouldn’t close properly. It was a real chore for the astronauts to wrench the hatch closed. In assessing what happened, NASA engineers wondered: Had the hatch undergone “cold welding?”
As Derek from Veritasium explains in the video below, “In space, if two metals come into contact, they can actually fuse together without the need for heat or melting of either piece.” As he promptly continues, this is not what happened to the hatch on Gemini IV. But it has happened on space missions, and it’s a real problem for metals we send into space.
Watch this video for a detailed explanation of how cold welding works, why it happens less than we might fear, and how it has actually occurred in space.
(Photo credit: NASA, via Wikimedia Commons.)
October 30, 2016 – 4:00am
Share Animal Illustrations and Fun Facts With These Colorable Postcards

Sharing trivia with friends has never been easier in our age of social media, but there’s still something charming about sending something through the mail. Amazing Animal Facts—previously a book and now a box of cards—allows you to send info-packed notes to your friends and family. The postcards feature animal-related facts along with illustrations by Sweden-based artist Maja Säfström.
The box set, which includes 50 cards, has five categories to choose from: sea, forest, field, jungle, and sky. Each card is dedicated to a different animal and comes with one to five different facts about the species. (For example, did you know that blue whales have belly buttons?) As a fun twist, all the cards are in black and white, so you can customize and color them to your liking. Once you finish coloring and adding a personal note, you can apply a stamp and pop it in the mail.
You can grab one of these sets on Amazon for $20.
Know of something you think we should cover? Email us at tips@mentalfloss.com.
October 30, 2016 – 12:00am
What’s in Citrus-Scented Air Fresheners? (Video)

In this installment of Ingredients, chemist George Zaidan digs into a key ingredient of many citrus-scented air fresheners: Limonene. In addition to being a killer band name, Limonene is found in citrus peels, and it happens to react with ozone to create formaldehyde.
Before we go nuts on this formaldehyde thing, it’s important to be clear that the amount of formaldehyde is low, and likely not an issue unless you’re going vastly overboard with ozone generators (like some “air cleaners”) and a lot of citrus-scented products. But it’s fascinating to explore how the chemical interplay between two otherwise innocuous consumer products—citrus-scented air fresheners and ozone-producing “air cleaners”—can create a really nasty substance.
For five minutes of useful chemistry advice, tune in:
For more on the issues Zaidan mentions with ozone-producing air cleaners, check the various links in the YouTube video description. If you’re more of a direct-link person, check out this explainer from the California E.P.A. or this PDF fact sheet from the Connecticut Department of Public Health.
October 29, 2016 – 8:00pm
How to Win the Oreo Twist Game Every Single Time

Oreo cookies are full of mysteries, not the least of which is the design of the wafer itself. But for many of us who’ve sat on either side of a cream-filled Oreo and twisted to see who got more of the delicious insides, another question has prevailed: What strategy, if any, can one apply to the game? We now have an answer, and it only took three Princeton University aerospace engineers to figure it out.
As Gizmodo reports, John Cannarella, Dan Quinn, and Joshua Spechler were graduate students in 2014 when they first started to consider the question surrounding the world’s most famous sandwich cookie. They did a bit of research and, when they found that no one had tackled the question, set to work hunting for an answer.
“It’s interesting from an engineering standpoint since the cookie is similar to many modern composites: a strong brittle layer (the wafer) for strength coupled with a weaker ductile layer (the cream) for toughness,” Cannarella told Quartz. “Shatterproof glass and batteries are other good examples of material systems that are mechanically analogous to Oreos.”
Sure, yeah, OK. But it’s also really important for winning playground face-offs in the ’90s.
To get a better sense of the physics at play, the team analyzed the cookie, putting it through rigorous experiments involving both robotic testers and real-life participants. They went through thousands of Oreos and, in the end, made a discovery that will help you win your cookie war every time: In any given box of Oreos, the cream ends up on the same side for every single cookie.
In other words, if you’re headed into battle, test a cookie from the box ahead of time. If you pull one out, twist it, and the cream is on side closest to the back of the box, that will be true for every cookie, in every row.
While Nabisco isn’t forthcoming about the cookie-making process, Quartz notes that a 2010 episode of How It’s Made has an illuminating look at the process behind Newman-O’s, which in turn helps to shed some light on the manufacturing methodology of Oreos. To assemble the sandwich cookies, a machine applies a dollop of cream onto one cookie and then finishes it with another. The physicists guess that the first wafer probably has a better hold on the cream (though there’s no way to be sure) and that ends up being the victory cookie in the twist game.
And there you have it. Go forth and share a cookie. Oh and we’re not necessarily saying you should employ the test cookie method to win, that would be cheating. We’re just the messengers here.
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October 29, 2016 – 4:00pm
Scientists found that men wearing white t-shirts…
Scientists found that men wearing white t-shirts with a large black letter “T” printed on the front were 12% more attractive to women. The t-shirt creates the illusion of broadened shoulders and a slim waist, a male body shape women typically find attractive.
As much as 7% of the population has experienced…
As much as 7% of the population has experienced waking from sleep and being totally paralyzed but aware as mind and body become out of sync in REM cycles.
Grab This Weekend’s Best Amazon Deals While You Can

As a recurring feature, our team combs the Web and shares some amazing Amazon deals we’ve turned up. Here’s what caught our eye today, October 29.
Mental Floss has affiliate relationships with certain retailers, including Amazon, and may receive a small percentage of any sale. But we only get commission on items you buy and don’t return, so we’re only happy if you’re happy. Good luck deal hunting!
GADGETS
Buffy the Vampire Slayer: The Complete Series for $48.99 (list price $199.98)
Photive CYREN II Wireless Waterproof Bluetooth Speaker for $34.95 (list price $99.95)
Samsung 32GB BAR USB 3.0 Flash Drive (MUF-32BA/AM) for $10.50 (list price $10.99)
Pulsar Men’s PXH705 Sport Stainless Steel Silver Dial Watch for $35.26 (list price $110.00)
KITCHEN
Ball Jars Collection Elite Wide Mouth Pint, Case of 4 for $4.89 (list price $11.99)
Tovolo Collapsible Microwave Cover for $7.99 (list price $9.99)
Nordic Ware Natural Aluminum Commercial Baker’s Half Sheet for $10.24 (list price $20.00)
Ceramic Cat Measuring Cups/ Baking Bowls for $27.23 (list price $34.50)
ORBLUE Chef’s Knife for $19.87 (list price $49.87)
Cuisinart 8-piece Ovenware Nonstick Roasting Set, Steel for $59.99 (list price $150.00)
George Foreman GRP1060B 4 Serving Removable Plate Grill, Black for $29.92
Vidalia Chop Wizard for $19.50 (list price $25.95)
Cooks Standard Stainless Steel Stockpot with Cover, 6-Quart for $26.56 (list price $49.99)
Rome’s 1805 Round Pie Iron with Steel and Wood Handles for $14.99 (list price $19.99)
Lenox Tuscany Classics Martini, Set of 4 for $39.95 (list price $54.00)
Bormioli Rocco Rock Bar Stackable Juice Glasses, 20 cl 6 3/4 0z, Set of 6 for $10.00
AmazonBasics Premium 8-Piece Steak Knife Set for $14.99 (list price $22.99)
Frazoni Nonstick Silicone Baking Mat, 28 x 42 cm, Red and White for $6.95 (list price $12.95)
Estilo Stainless Steel Lazy Susan – 2 Tier Design, 360-degree Turntable for $12.99
Yeti Coolers Rambler Colster, 12oz for $27.00 (list price $29.99)
Kitchen Gizmo SNAP’N STRAIN strainer for $12.99 (list price $19.99)
Lodge ASHH41 Silicone Hot Handle Holder, Red for $5.99 (list price $8.81)
Lodge L9OG3 Cast Iron Round Griddle, Pre-Seasoned, 10.5-inch for $13.19 (list price $24.00)
Pyrex Easy Grab 8-Piece Glass Bakeware and Food Storage Set for $15.86 (list price $48.99)
Resource for Cooking Stainless Steel Manual Can Opener for $7.99 (list price $39.99)
HOME
Dyson DC39 Ball Multifloor Canister Vacuum (Certified Refurbished) for $179.99 (list price $299.99)
Ettore 17012 All-Purpose Squeegee, 12-Inch for $4.82 (list price $19.56)
Lasko 4443 40″ Hybrid Fan for $64.80 (list price $77.99)
Big Joe XL Fuf in Comfort Suede, Espresso for $129.41 (list price $199.99)
Atlantic 33950212 Gaming Desk Pro for $118.74 (list price $169.99)
AcuRite 00325 Home Comfort Monitor, Black for $8.49 (list price $11.99)
Vornado Flippi V8 Personal Air Circulator for $28.95 (list price $49.99)
Whitmor Closet Organizer with 2 Shelves for $19.99 (list price $39.99)
OXO Good Grips Deep Clean Brush Set for $5.99
OXO Good Grips Extendable Tub and Tile Scrubber for $12.99
Marquis by Waterford Sparkle 9-Inch Bowl for $29.85 (list price $100.00)
Whitmor Wood Suit Hangers, Set of 16, Natural for $16.39 (list price $24.99)
HEALTH AND BEAUTY
Art Naturals Detangling Hair Brush Set (Pink and Black) for $8.95 (list price $15.00)
L’Oreal Paris Excellence Creme Hair Color, 4 Dark Brown for $7.17 (list price $8.99)
RUIMIO Lighted Makeup Mirror with 7X Magnification and Suction Base for $29.99 (list price $49.99)
Panasonic ER-GN30-K Nose Ear Hair Trimmer for $14.99 (list price $19.99)
Aveeno Active Naturals Daily Moisturizing Lotion, 18 Ounce for $6.05 (list price $15.18)
Men’s Rogaine Foam, Three Month Supply for $39.74 (list price $50.13)
Gillette Venus Embrace Women’s Razor Blade Refills 4 Count for $16.04 (list price $20.49)
Simple Cleansing Facial Wipes, Kind to Skin 25 Count, Twin Pack for $6.83 (list price $8.39)
Dove Men+Care Body Wash, Extra Fresh 23.5 oz for $6.29 (list price $9.19)
Dove Body Wash, Sensitive Skin Pump 34 Ounce for $7.62 (list price $12.09)
Radha Beauty Vitamin C Anti-aging Serum, 2 fl oz for $15.95 (list price $49.99)
Dove Beauty Bar, Sensitive Skin 4 oz, 16 Bar for $15.66 (list price $25.09)
Philips Norelco HQ8 Dual Precision Replacement Heads for $21.88 (list price $36.99)
It’s a 10 Miracle Leave-In Product, 10-Ounce Bottle for $22.73 (list price $35.94)
Conair 1875 Watt Hair Dryer for $12.99 (list price $16.99)
American Crew Fiber Pliable Molding Creme For Men 3 Ounces for $9.92 (list price $15.00)
Dove Refresh + Care Dry Shampoo, Volume & Fullness 5 oz for $6.59
Neutrogena, Anti-Residue Shampoo, 6 fl oz for $4.83 (list price $9.25)
OFFICE, SCHOOL, AND CRAFTS
Staedtler Calligraphy Pen Set, 33 Pieces for $15.31 (list price $21.89)
Singer Polyester Thread, Assorted Colors, 24 Spools for $2.00 (list price $3.89)
Gingher 3.5 Inch Stork Embroidery Scissors (01-005280) for $16.49 (list price $19.99)
Emojistickers Most Popular Emojis, 288 Pack for $1.94
Fiskars 8 Inch Everyday Titanium Scissors, 2 pack for $8.54 (list price $24.99)
Sargent Art 22-1501 10-Count Glitter Gel Pens for $5.59
Spectrum Diversified 11200 Large Rectangle Bookends, White for $24.89 (list price $27.00)
Expo 2 Low-Odor Dry Erase Markers, Chisel Tip, 16-Pack, Assorted for $11.02 (list price $24.99)
OUTDOORS, GARDEN, AND SPORTS
Fatwood Firestarter 9912 0.25 Cubic Feet Fatwood for Fireplace in Burlap Bag, 10-Pound for $25.85
Viking 912600 8-Way Heavy Duty Spray Nozzle for $6.36 (list price $7.79)
Repel Easy Touch Umbrella DuPont Teflon Travel Umbrella, Black for $23.95 (list price $49.99)
Lewis N. Clark Travel Comfort Set, Black, One Size for $15.28 (list price $19.99)
Bowflex SelectTech 552 Adjustable Dumbbells (Pair) for $259.99 (list price $549.00)
Nature’s Miracle Stain & Odor Remover, Orange Oxy, Gallon (5162) for $20.39 (list price $44.26)
Fiskars 29 Inch Machete Axe for $36.04 (list price $54.99)
ELECTRONICS
Logitech Wireless Mouse M320, Black for $17.85 (list price $29.99)
TP-Link N300 Wi-Fi Range Extender (TL-WA855RE) for $19.95 (list price $29.99)
eSecure All-in-1 USB Card Reader for all Digital Memory Cards for $7.19 (list price $29.99)
Belkin QODE Ultimate Keyboard Case for iPad Air 2 (White) for $53.30 (list price $129.99)
Panda Wireless PAU06 300Mbps N USB Adapter for $19.99 (list price $29.99)
TOOLS
Amprobe BAT-200 Battery Tester for $6.26 (list price $7.95)
Stanley 68-010 Multibit Ratcheting Screwdriver with 10 Assorted Bits for $8.88 (list price $20.12)
SpeedOut Damaged Screw Extractor & Bolt Extractor Set for $6.99 (list price $19.99)
DEWALT DW2530 35 Piece Magnetic Compact Rapid Load Set for $23.99 (list price $53.24)
Stanley 12-920 6-1/4-Inch Contractor Grade Block Plane for $31.58 (list price $61.08)
Gorilla Super Glue Brush & Nozzle, 10 g, Clear for $5.49
Albrillo E12 400 Lumens 5W LED Bulb, 4-Pack for $14.99 (list price $59.99)
Makita T-01725 Impact Drill-Driver Bit Set, Black Oxide, 70-Piece for $22.99 (list price $45.00)
BOSTITCH BTST514150 Open Mouth Tool Bag, 14-Inch for $14.97 (list price $24.20)
Stanley 46-071 Premium Quick Square Layout Tool, 7″ for $5.97 (list price $10.30)
Hillman Fastener Corp 130251 Picture Hanger Assortment Kit for $8.84 (list price $9.99)
October 29, 2016 – 11:00am