Category: Science

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A Man’s Strange Reaction to Antibiotics Has His Guts Brewing Alcohol

Well, this is odd.

A week into his course of cephalexin, a common antibiotic prescribed to ward off infection in an injured thumb, a man checked into the emergency room with some strange symptoms.

They included memory loss, brain fog, and episodes of depression, along with personality changes and uncharacteristic aggression.

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Among my sleep studies research there are numerous notes about how alcohol disrupts sleep. Because it causes the brain to be simultaneously in alpha and delta activity patterns (one’s for being wide awake, the other for being in deep sleep), and blocks REM sleep, and messes with adenosine production interrupting your circadian rhythm, and aggravating breathing problems such as snoring and sleep apnea. . This has me thinking about a recently-discovered, seemingly-rare condition known as auto brewery/gut fermentation syndrome. It’s a condition in which the naturally-occurring yeast in your gut causes the sugars you consume to ferment into alcohol. Known cases lead to folks becoming drunk as a result of drinking fruit juice (for example), but — as with any condition — there should be cases that run the gambit between in-your-face (drunkenness) and subtle-enough-to-be-misdiagnosed-as-a-dozen-other-things-if-at-all. . With this in mind: What if an individual’s daily sugar intake, daily energy use, and overall gut yeast levels are balanced in such a way that their gut doesn’t automatically create alcohol during the day, but then at night (with some sugars still in the system and physical activity coming to a halt) the gut then creates alcohol? That person would have no trouble falling asleep, but would regularly have trouble staying asleep. . It’s just a theory. But it’s a theory that can be checked (at least on the individual level) via stool test and or glucose challenge test. And for those struggling to get a proper diagnosis for sleep issues, those are tests worth taking. . If it turns out a person has secondary insomnia resulting from auto brewery syndrome, that means there’s only a handful of underlying conditions that could be causing the whole kit-n-kaboodle. Because no one’s born with auto brewery syndrome, it arises as a result of some other condition creating too much yeast in your gut. And that really helps to narrow down the possibilities. . And as someone whose OCD was misdiagnosed and punished in equal measure for about 25 years before we finally knew what was what, if even one random-ass theory can help someone get to the right diagnosis a little fast

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Doctors were unable to get to the root of the cause, and he suffered those same symptoms for some time. Three years later, a psychiatrist treated him with antidepressants, but his issues persisted.

Things came to a head when he was pulled over on suspicion of drink driving, and was found to have a blood-alcohol level of 200mg/dL (about the equivalent of 7-10 drinks, depending on your weight). He was nauseous, vomiting, impaired, had no memory of the event, and passed out in the hospital.

The patient, however, insisted he had not had one single drink.

It was his aunt who brought him a breathalyzer, and as he tracked his measurements over time, he received similar readings.

A doctor in Ohio administered a carbohydrate test, where the patient consumes carbohydrates and then has their blood-alcohol levels monitored over the course of several hours, and found elevated alcohol levels in his blood. They also found brewer’s yeast in his stool, and eventually diagnosed him with auto-brewery syndrome (ABS).

The syndrome, also known as gut fermentation syndrome, is extremely rare. It causes the digestive system to produce ethanol that makes you intoxicated. Several cases have been reported over the years, usually discovered under similar circumstances (people arrested for drunk driving without having a drink).

This man, however, is the first documented case of ABS stemming from a course of antibiotics.

“We postulate that the antibiotic altered his gut microbiome, allowing fungal growth. This diagnosis should be considered in any patient with positive manifestations of alcohol toxicity who denies alcohol ingestion.”

He was given antifungal medications and, despite a relapse after a night of pizza and soda, is doing well.

I’m not saying this will work if you ever find yourself on the wrong end of a traffic stop, but I mean. It could be your guts making beer, and you just don’t know it.

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This Is Kind of Scary. Antibiotic Resistance in Germs Has Doubled in the past 20 Years.

There are a lot of things to worry about these days, but if you’re a germophobe (like my husband) or someone obsessed with the idea that we’re all going to die in a pandemic (like me), then you’ve probably spent at least some time wondering what’s going to happen when antibiotics stop being widely effective.

I mean…the world before antibiotics was a pretty harrowing place.

And now, research is finding that the number of cases in which people experience infections that are resistant to antibiotics is sharply on the rise.

Preliminary findings, which were presented at United European Gastroenterology Week Barcelona 2019, focused on conditions related to the Helicobacter pylori bacteria – gastric ulcer, lymphoma, and gastric cancer – and found that resistance to the typical antibiotic treatment has risen to nearly 21.6% (from 9.9% in 1998).

 

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Similar rises have been seen with other common antibiotic treatments.

Antibiotic resistance happens when bacteria evolve a tolerance to the drugs we use to eliminate them from our bodies body. Recently, the issue has gotten attention from the WHO, as well as national and regional health organizations in the U.S. and the EU.

 

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Right now, around 56,000 people die worldwide every year when antibiotics fail to treat their infections. Of course, according to this research, we can expect that number to rise, says lead author Francis Megraud.

“With resistance rates to commonly used antibiotics such as clarithromycin increasing at an alarming rate of nearly 1% per year, treatment options for H. pylori will become progressively limited and ineffective if novel treatment strategies remain undeveloped. The reduced efficacy of current therapies could maintain the high incidence rates of gastric cancer and other conditions such as peptic ulcer disease if drug resistance continues to increase at this pace.”

 

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Not being able to counter the effects of H. pylori is especially telling – and bad, as children are often the ones infected.

“The findings of this study are certainly concerning, as H. pylori is the main cause of peptic disease and gastric cancer. The increasing risk of H. pylori to a number of commonly-used antibiotics may jeopardize prevention strategies.”

If you’re worried about yourself or your family, the best thing you can do is not take antibiotics for infections that are likely viral, not all that bothersome, or will run their course on their own without excessive discomfort.

Easier said than done, I know, but you’ll be toughing out a lot worse if these bacteria evolve faster than we do.

Real talk.

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10 Interesting Facts to Help You Get Through This Loooooong Week

Will this week ever end.

It feels like it’s taking FOREVER.

But, wait! I have a good idea about how to fix this.

Facts! Great facts that will challenge your brain and soothe your soul.

Let’s get started!

1. It’s mostly water weight.

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2. Rejection leads to later problems.

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3. That’s totally disgusting! Yay humans!

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4. Oh, it’s real…

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5. Typical male behavior.

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6. Are you good at this?

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7. This is amazing.

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8. Be on the lookout…

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9. A symbol of grace and poise.

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10. Wow…that’s really something…

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That’s a little better, right?

Now let’s power through the rest of this damn work week together!

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People Share What They Think Are the Worst Legal Things You Can Do

You can do a lot of terrible things in this world that are totally legal.

Things that most of us would never dream of doing. And they might infuriate you…

AskReddit users shared their thoughts on the subject.

1. That’s pretty infuriating.

“You can leak the names, addresses, email addresses, social security numbers, driver’s license numbers, and payment card details of nearly half of all Americans (and more than half of all American adults) and then settle for about $5/person.”

2. Makes my blood boil.

“Permanently destroying huge swaths of land.

There’s a development corporation in my hometown that has bought up virtually all of the remaining woods, meadows and wetlands in the area, paved them, and built retail spaces that go vacant just a few months later.

Businesses aren’t even moving into these “office parks”, but the group just keeps spreading out and “developing”. It seems like every month, I drive past another leveled tract of land.”

3. Whoa, that’s kind of intense.

“Groom your stepdaughter for over a decade, then when she’s 18, divorce her mom and hook up with your stepdaughter.”

4. It is pretty bad.

“I think it’s pretty shitty to claim bodily harm from a very minor car accident just to get 10k, and make the other person pay more for their car insurance. I’m looking at you, lady I hit going 3 mph.

Probably not the worst thing, but it’s pretty bad.”

5. Who the hell does this?

“Take custody of a pet in a divorce and the. Put the pet down out of spite.”

6. Ouch…

“Recruit people to join Scientology.”

7. If not…that…

“Is it illegal to leave your shopping cart in the parking lot instead of returning it to the corral? If not, that.”

8. People are pretty sh*tty.

“Sue your poorer ex spouse for child custody so repeatedly that you drain their finances and can’t fight it anymore.”

9. A lot of this out there.

“Steal people’s money through fine print conditions.”

10. Not a good idea.

“Ruin the world economy by handing out subprime loans.”

11. That’s not cool.

“Nestle claiming rights to water and then selling it back to the public at exorbitant prices all while polluting the earth with the production of single-use plastic bottles.”

12. Sign of the times.

“Fire all your employees and move your business to East Asia so you can essentially use slave labor.”

13. Does this sound familiar?

“Start a pharmaceutical company.

Develop a drug that people need to live.

Raise the price just because you know they’ll pay for it if they don’t want to die.”

14. Bullying and abusing.

“Bully someone. Mentally abuse someone. Making them feel bad about themselves their whole life.”

15. Vaccines do not cause autism.

“Not vaccinating your kids.”

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Here Are the 20 Companies That Produce over 1/3 of the World’s Total Greenhouse Gas Emissions

Many people and governments and companies around the world are doing their best to mitigate some of the effects their lives and business dealings have on the planet, so that hopefully we can have a future that doesn’t include a complete apocalypse and the extinction of human beings.

These 20 companies, though, appear to not give a rat’s a** how much they harm future generations, as long as they’re still making the big bucks.

 

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According to the Climate Accountability Institute, a handful of oil, gas, and coal companies are responsible for 480 billion tonnes of carbon dioxide and energy-related methane pumped into Earth’s atmosphere since 1965 – that’s 35% of all greenhouse gas emissions since then.

The report also states that half of all greenhouse gas emissions in recorded history have been released into the atmosphere since 1990, with 1.35 trillion tonnes of carbon dioxide (or equivalent GHGs) emitted since 1965.

 

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The CAI had this to say about their findings in a recent press release:

“Although global consumers from individuals to corporations are the ultimate emitters of carbon dioxide, we focus on the fossil fuel companies that, in our view, have produced and marketed the carbon fuels to billions of consumers with the knowledge that their use as intended will worsen the climate crisis.”

Here’s a list, from worst to…less worse.

20. Saudi Aramco (Saudi Arabia) — 4.38 percent
19. Chevron (USA) — 3.2 percent
18. Gazprom (Russia) — 3.19 percent
17. ExxonMobile (USA) — 3.09 percent
16. National Iranian Oil Co. (Iran) — 2.63 percent
15. BP (UK) — 2.51 percent
14. Royal Dutch Shell (The Netherlands) — 2.36 percent
13. Coal India (India) — 1.71 percent
12. Pemex (Mexico) — 1.67 percent
11. Petroleos de Venezuela (Venezuela) — 1.16 percent
10. PetroChina/China Natl Petroleum (China) — 1.15 percent
9. Peabody Energy (USA) — 1.14 percent
8. ConocoPhillips (USA) — 1.12 percent
7. Abu Dhabi (UAE) — 1.01 percent
6. Kuwait Petroleum Corp (Kuwait) — 1 percent
5. Iraq National Oil Co. (Iraq) — 0.93 percent
4. Total SA (France) — 0.91 percent
3. Sonatrach (Algeria) — 0.91 percent
2. BHP Billiton (Australia) — 0.72 percent
1. Petrobras (Brazil) — 0.64 percent

If we hope to achieve the goals set by the Paris Climate Change Agreement in 2017, all of these companies would have to recognize their current levels as a “peak” and immediately begin to taper them. The report says that these fossil fuel giants, and others like them, have “a significant moral, financial, and legal responsibility to help curtail and compensate for the runaway effects of climate change.”

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Without action now, climate change will exacerbate the inequalities that children already face, and future generations will suffer. On our 5th anniversary Pressman's pledges to donate 50% of the total Dine-in Sales at all outlets to Emirates Nature WWF towards the cause of Climate Change. Join us on 3rd November. #pressmansforenvironment #pressmansanniversary #youthforclimate #climatejustice #climatechangeisreal #globalwarming #strikeforclimate #connect2earth #environment #voicefortheplanet #ourplanet #naturealert #makeahealthyplanet #savetheplanet #climatechange #climatecrisis #lowcarbonfuture #saynotofossilfuels #saveenergy #savetrees #savewildlife #supportemiratesnature #emiratesnature #saveourplanet #zomatouae #deliveroo_ae #talabatuae #ubereats_uae #dubai #uae

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It’s time for people to stop plowing ahead like horses plodding a field with blinders on, eyes on nothing but the row of money to be reaped ahead. If the world wants to survive long enough to leave something other than smoking ashes for our kids, the time is nigh to stop, look around, and start to take several million steps back.

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Take a Look at This Giant Ocean Cleaning Device That Removes Plastic Waste from the Water

There is a giant swath of floating garbage (we’re talking twice the size of Texas) in the Pacific called the Great Pacific Garbage Patch. Thousands of tons of plastic debris is brought together by swirling ocean currents and kept in place by those same forces.

Aside: Is this where Garbage Pail Kids are born? We need to investigate.

Plastic and other trash, like discarded fishing nets, pose large and often deadly issues for marine life, a sad fact that has convinced scientists and conservationists that we need to fix the problem.

Now, there may be an answer.

The Guardian reports that the non-profit Ocean Cleanup has engineered a giant, floating device that can remove plastics safely from the water. They’ve been working on the device for seven years, but only recently put it into action with positive results.

The cleaner captures trash with a large folding arm, everything from large cartons, crates, and other fishing gear, to tiny microplastics as small as a millimeter wide. Its U-shaped barrier drops a net below the surface and, as the current moves, traps pieces of trash moving along at a good clip.

Fish, if you’re worried, are able to swim beneath it.

Ocean Cleanup founder and CEO Boyan Slat confirmed at a press conference that the invention is “catching plastics,” and tweeted out a picture of all of the collected debris.

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Das System @theoceancleanup macht sich die natürlichen Ozeanströme zu nutzen um Müll zu sammeln und zu konzentrieren. Es besteht aus langen, luftgefüllten Schläuchen aus Gummi, die an der Wasseroberfläche schwimmen und Plastikmüll auffangen. So kann der angesammelte Abfall abgetragen und entsorgt werden. ♻ Seit 2016 wird das System immer wieder in unterschiedlichen Meeren getestet. Zunächst in der Nordsee und seit 2017 auch vor der kalifornischen Küste. Die gesammelten Informationen und Erfahrungen halfen The Ocean Cleanup weiterzuentwickeln und zu verbessern. 2018 startete endlich das große Sammelsystem, welches 2019 erneut verbessert wurde und nun erfolgreich Plastikmüll sammelt! Sollten die Ergebnisse weiterhin positiv bleiben wird das System an weiteren Orten der Welt eingesetzt. Übrigens ist das System für Fische ungefährlich, da diese einfach darunter hindurch schwimmen können. ? Folge uns für aktuelle Infos und Trends zur Plastikvermeidung ✅ Quelle: https://theoceancleanup.com ? #theoceancleanup #oceancleanup #oceancleanupproject #müllsammeln #müllsammelaktion #plastikfrei #plastikvermeiden #plastiksammeln

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“Our ocean cleanup system is now finally catching plastic, from one-ton ghost nets to tiny microplastics! Also, anyone missing a wheel?”

The process of developing the device has taken most of Boyan’s adult life – he presented the idea at a TEDx talk when he was just 18, and it has gone through many failed attempts before finally reaching this sweet success.

The team learned from the various mistakes, and they are now able to capture even more types and sizes of plastics than they first imagined. It’s easy to pick up on their excitement in this statement:

“Our team has remained steadfast in its determination to solve immense technical challenges to arrive at this point. Though we still have much more work to do, I am eternally grateful for the team’s commitment and dedication to the mission and look forward to continuing to the next phase of development.”

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001 B successfully completed the clean up test!

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Ocean Cleanup is going to start improving their device based on what they learned during this exercise, including work on a full-scale cleanup device that can endure tough conditions and have enough space to store large amounts of collected plastics while at sea.

Good people going good work. May there be more of them coming up through the ranks.

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The Science Behind Your Morning Trip to the Bathroom

Whatever you want to call it, many of us head to the bathroom to take care of it first thing in the morning (or at least, after your morning coffee).

And it turns out there’s a reason that many of us get the urge at the start of the day – it’s science.

According to gastroenterologist Dr. Sarina Psricha, morning is the best time to have a bowel movement because it’s the time of day when your body is best equipped to evacuate.

 

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“In the morning, when we first wake up, an internal alarm clock goes off in our colon, and the colon starts contracting more vigorously. In fact, the colon contracts and squeezes three times as hard in the first hour we are awake compared to when we are sleeping.”

Your small intestine and colon work to process any food leftover from the day before as you sleep, and that’s why the urge sets in about 30 minutes after you wake up. Add in stretching, having a drink of water or coffee, and voila – bowel movement!

“Drinking early morning coffee works synergistically with gut motility to create healthy bowel movements.”

If you’re not a coffee person, try warm saltwater with lemon if you’re having trouble getting things moving.

 

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If you find yourself wondering if your bowel movements are normal, and the good news is that, even if you don’t head to the pot first thing in the morning, there’s probably nothing to worry about. There’s a large range of what is considered “normal”: anywhere from three times a week to three times a day. Plus, factors like diet, exercise, and travel can alter your regular schedule.

 

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“Typically, the best time of the day to have a bowel movement is in the morning. However, some people may not have morning bowel movements and this does not necessarily mean there are any issues. It is okay not to have morning bowel movements as long as people are having regular daily bowel movements.”

There it is – all you ever wanted to know about your morning dump (and probably a whole lot more).

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This Is How the Earth Got Its Name

It’s pretty obvious, especially if you’ve ever read any Greek and Roman mythology, how most of the planets (Mercury, Mars, Venus, Saturn, and the rest) in our solar system got their names, but what about Earth?

There’s no Roman or Greek god named Earth, I’m pretty sure.

Image Credit: Pixabay

You might not know that there’s a different word for our planet in other languages – terra (Portuguese), dunya (Turkish), and aarde (Dutch), to name a few – but that each word is, like Earth, derived from a root word meaning ‘ground,’ or ‘soil.’

The use of the word ‘earth’ goes back around 1,000 years (that we know of), to when English was evolving from Anglo-Saxon as Germanic tribes spread from Europe into Britain. The Anglo-Saxon word for ‘earth’ was ‘erda‘ and the German equivalent ‘erde,’ both meaning ground or soil.

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In Old English, the words became ‘eorthe‘ or ‘ertha.‘ Over the next millennium, we get the word ‘earth’ to mean soil – eventually it came to mean the planet as a whole.

Earth is definitely the only planet name that was never connected to Greco-Roman mythology, which might perhaps be because the other planets were discovered over time, whereas people have always lived on the earth. Translations of the Bible also support the fact that our planet was never referred to by any word that meant something other than the land itself.

Image Credit: Pixabay

And now you know – just wait until you can drop some of this etymology at your next dinner party!

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Check out the Air-Breathing Snakehead Fish That’s Invading Georgia

If you’ve ever wondered what it’s going to look like when nature finally rises up to finish off human beings once and for all, well, this air-breathing fish that’s able to trade water for land seems like a good candidate.

It’s called the Northern Snakehead, and wildlife officials in Georgia are advising residents to kill them on sight.

 

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The fish, which can breathe air long enough to traverse short distances on land, is not native to North America. That means it’s invasive, and can easily upset local ecosystems by outcompeting endemic species for food and habitats if it is allowed to reproduce and spread unchecked.

There are several varieties of snakehead fish – this particular one is native to East Asia, not in privately owned ponds in Gwinnett County, Georgia, where the first one was spotted.

 

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The fish is nightmarishly long – it can reach up to 3 feet in length – and a mottled or splotchy brown color. If you catch or see one, the Georgia Department of Natural Resources’ Wildlife Resources Division would like you to kill it and then freeze it until someone from the agency’s fisheries office can come and collect it.

 

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No one knows for sure how it first arrived in North America, or in Georgia specifically, but the aquarium trade or the food industry are the most likely culprits.

Georgia is not alone in this battle – varieties of snakehead have been spotted in 14 states so far.

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Highly Superior Autobiographical Memory (HSAM) Is a Rare but Real Condition

The few people who have highly superior autobiographical memory (HSAM) can tell you exactly what happened on any given day, down to the way they felt and at what time. It’s both a superpower and a curse, depending on the circumstances. And to this day, scientists have no idea what contributors make a person have HSAM.

Though they do have some theories.

In 2006, a case study of  Jill Price, referred to by the pseudonym AJ in the study, was published in Neurocase. It described in detail her unusual memory. Price later outed herself as AJ publicly.

In an email, Price explained her ability:

I can take a date, between 1974 and today, and tell you what day it falls on, what I was doing that day and if anything of great importance (i.e.: The Challenger Explosion, Tuesday, January 28, 1986) occurred on that day I can describe that to you as well …Whenever I see a date flash on the television (or anywhere else for that matter) I automatically go back to that day and remember where I was, what I was doing, what day it fell on and on and on and on and on. It is non-stop, uncontrollable and totally exhausting.

And she wasn’t alone. A number of people came forward after the report, saying they had the same ability. Some were tested and found to have HSAM, same as Price.

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Currently, only about 60 people worldwide are believed to have HSAM. Scientists are working with them to see if they can learn more about the average person’s memory, as well as how, and why, their super memories operate the way they do.

Something researchers have uncovered is that people with HSAM tend toward obsessiveness with cleaning, collecting and organizing, so there is thinking that perhaps collecting and organizing memories is part of HSAM.

Photo Credit: Pixabay

Also, structural differences in the areas of the brain associated with autobiographical memory creation show up on scans. When asked about particular dates from the past, regular people lose their ability to recall them after about a week. People with HSAM recall details up to a decade and longer.

Something else researchers found was that people with HSAM can recall false memories just as often as regular people. So, their superhuman memories are far from perfect.

Photo Credit: Pexels

So, what does this all mean? Maybe the answer lies in the mysterious part of the brain where we turn short-term memories into long-term memory.

It would be interesting to figure out, although where this could have practical applications for those of us with normal to poor memories remains to be seen.

I kind of like living my life able to forget – at least I don’t remember all my regrets…

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