Scientists Have Found a Way to Reverse Aging – In a Lab

Sorry, cosmetics insudtry, but I’m afraid we’ve got some bad news. As for everyone else…it’s time to celebrate! A group of scientists recently published a study in the journal Aging that describes how they were able to make old cells regain the dividing ability of younger cells.

Researchers have been looking into the process of aging in humans for decades, trying to pinpoint when and how things begin to change and degrade, and while this new experiment doesn’t claim to be able to reverse aging, it does claim to have had success in stopping the aging process before it passes the point of no return.

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That is, the point at which cells become stagnant and start to degrade instead of duplicate. It’s important because some researchers believe the accumulation of the stagnant cells in our organs is the key to unlocking the process of aging.

“We still don’t fully understand why cells become senescent as we age, but damage to DNA, exposure to inflammation and damage to the protective molecules at the end of the chromosomes – the telomeres – have all been suggested,” said the authors in a post on The Conversation. “More recently, people have suggested that one driver of senescence may be loss of our ability to turn genes on and off at the right time and in the right place.”

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Their process included delivering hydrogen sulfide directly to mitochondria. Researchers believe the presence of the hydrogen sulfide molecule in the mitochondria can increase certain splicing factors, which are proteins that switch genes on and off in response to their environment.

The scientists concluded, “We are hopeful that in using molecular tools such as this, we will be able to eventually remove senescent cells in living people, which may allow us to target multiple age-related diseases at once. This is some way in the future yet, but it’s an exciting start.”

Photo Credit: Pixabay

I imagine that, when the time comes for human trials, they won’t have any trouble lining up volunteers. Not many people wouldn’t want to be the tribute in the game of figuring out how to stop the aging process, once and for all.

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These Rejection Stories from Creative People on Twitter Give Us All Hope

To work in a creative field means to experience rejection. Lots of it. That’s just part of the job. Whether you are a writer, artist, painter, singer, or musician…things can get discouraging. But it’s important to never lose hope.

Poet and author Saeed Jones shared own of his own rejection experiences and it inspired other creatives to share their personal tales.

So if you’re feeling down about constantly hearing the word “no”, remember that every successful person has been there many times.

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There’s an Ideal Time to Go Shopping If You Want to Avoid Lines and Save Money

If you go at the wrong time, grocery shopping can be the most stressful experience in the world. The parking lot is full, the aisles are crowded, it’s enough to make a person have a meltdown by the frozen food. And if that wasn’t all bad enough, you might be paying more than you should. According to Ibotta, many items are priced above average on the weekend.

Photo Credit: Unsplash,rawpixel

Ibotta, a shopping app, determined that you should avoid Saturdays and Sundays and stick to grocery shopping on weekdays if you want to save some money.

Photo Credit: Pixabay

Here are some of the things Ibotta discovered when they crunched the numbers. Wine is 4% cheaper on Tuesdays. On Wednesdays, beer is 1% cheaper on average and bread goes down by 2%. For you veggie lovers, produce is 3% cheaper on Hump Day.

Photo Credit: Max Pixel

And here’s a huge one: on Fridays, ice cream is down 1%. If you want a stress-free shopping experience, go on Tuesday and Wednesday mornings when the stores will be the least crowded. So now that you’re armed with this information, plan your trips to the grocery store for maximum privacy and to save some cold, hard cash.

Photo Credit: Pixabay

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History Buffs Explain 18 of the Best Plot Twists in History

Anyone who’s studied history knows that it’s just a bunch of crazy stories. There’s lying, cheating, stealing, and plenty of plot twists.

So let the internet history buffs take you by the hand and lead you down the beautiful path of weird, wild, and unbelievable moments in the past – some of which changed the world.

#18. The horse’s asshole.

“When Troy thought the Greeks had given them a cool horse statue to make peace with them but the Greeks came out of the horse’s asshole and murdered everyone in their sleep. Rude.”

#17. All for the crown.

“Jean Bernadotte.

Guy was appointed Marshall of France by Napoleon, got offered the throne of Sweden, accepted it, joined with England and helped defeat Napoleon, and his descendants are still the Swedish royale family.”

#16. On idolization.

“Miracle of the House Brandenburg

It’s the Seven Years War. Frederick the Great, King of Prussia, is defeated decisively at the Battle of Kunersdorf by the combined forces of his enemies, losing more than half his army. His enemies, the Russians are advancing on Berlin from the East, the Austrians are closing in from the South. Frederick manages to gather 30,000 men for the defense of Berlin against a force of more than 90,000. The situation is completely dire and Frederick is making plans to either die in the defense of his capital or take poison. He wrote of his enemies, “We’ll fight them – more in order to die beneath the walls of our own city than through any hope of beating them.” And then the enemies who were closing in for final victory… just stopped, turned around, and went home.

What happened at that moment that prevented the Russians and Austrians from reaching their goal? They had also taken heavy losses at Kunersdorf and decided they had over-extended themselves in a rapid advance, began to worry about their supply lines and their ability to occupy Berlin and so they just withdrew to fight another day.

Then, later in the war. Prussia’s position turns bleak again. Frederick is again surrounded and isolated. When suddenly the Russian Tsarina dies and is replaced by her nephew, who in a strange twist, is a complete Prussophile and admirer of Frederick’s. He once wrote to Frederick that he would rather be a colonel in the Prussian army than to be the Tsar of Russia. Of course not wanting to be the one to destroy his idol, the new Tsar turns Russia’s armies around and signs a peace treaty with Frederick.”

#15. Washington’s humility.

“They say, George Washington’s yielding his power and stepping away.

The story I remember that illustrates that:

The American-born painter Benjamin West was in England painting the portrait of King George III. When the King asked what General Washington planned to do now that he had won the war. West replied: “They say he will return to his farm.”

King George exclaimed: “If he does that, he will be the greatest man in the world.”

#14. Bleak.

“The United States assisting in the overthrow of the democratically elected leader of Iran which lead to the country hating and mistrusting is to this day.”

#13. Napoleon and the rabbits.

“After the signing of the Peace of Tilsit in 1807, Napoleon was feeling pretty damn happy. So, to celebrate, he got his trusted chief-of-staff, Berthier, to organise an afternoon of rabbit shooting for the Imperial Court to enjoy. Berthier, being keen to impress Napoleon, bought thousands of rabbits to ensure that they’d all be entertained for the afternoon.

So, afternoon came and the rabbits were brought out for the shooting. That should’ve been fine, right?

Nope. Berthier made a little mistake with the rabbits he chose. He’d chosen tame rabbits rather than wild rabbits. Because of that, they thought they were about to be fed rather than killed. So, rather than fleeing for their lives, they mistook Napoleon for their keeper and began to run towards him at 35mph.

The shooting party were unable to do anything to stop the thousands of rabbits running after Napoleon. So, Napoleon’s only option was to run away from the rabbits and try and beat some of them off with his bare hands. He was outnumbered, though, and was driven back to his carriage while other people thrashed at the rabbits with horsewhips. As you can guess, it took quite a while to get the rabbits to calm down.”

#12. It all happened by accident.

“Columbus sailing west to try to reach the east only to instead stumble across the new world. Although it would have happened at some point anyway, the discovery of the new world by the Europeans in 1492 is arguably one of the most important events in world history, one which changed the course of history: and it all happened by accident.”

#11. Booze 1, Mormons 0.

“How San Francisco escaped being taken over by the Mormons.

Back when it was Yerba Buena a ship of 150 Mormons (mostly women) arrived with intentions to set up a Mormon state. Yerba Buena was only about 50 people.

But Mr. Brannon, their leader found out about Sutter’s gold, became California’s first millionaire, abandoned the Mormons, became an alcoholic, and died pennyless.”

#10. Poor Napoleon… You know what? Nevermind.

“Napoleon losing the battle of Waterloo due to the pain/irritation from his hemorrhoids. The battle has been war-gamed countless times and in most instances the French win easily. However Napoleon was slow to react and often went back into his tent for some “alone-time’. “Napoleon was indeed suffering from the affliction, which “had prolapsed and were strangulated outside the anus,” causing him great pain”. (This information came from the emperor’s brother, Jerome, one of only three people aware of Napoleon’s condition; Jerome shared the story in 1860, shortly before his own death.)”

#9. LBJ.

“Racist white southerner passes all the civil rights legislation JFK dragged his feet on for a thousand days in six months.

Bonus Plot twist: JFK is still the one who gets his portrait placed beside MLK’s in black homes across America.”

#8. A force of nature.

“The fact that the mongol invasion of Japan was stopped not once, but twice, by typhoons savaging their fleet.”

#7. And again…

“In August of 1814 British troops occupied and burned many of the public buildings in Washington DC (War of 1812).

A freak storm extinguished most of the fires and caused the British to withdraw.”

#6. On underestimating the Germans.

“Imagine you’re France, Belgium or the UK after the Great War.

You dealt with some ambitious Germans, but you fought them back and shut them down. Even though you have deals in place to keep them from regaining power, you don’t take your chances, and decide to invest in armies and defenses that can stop future German aggression.

Your plan is fool proof. You take the most vulnerable part of your border and build the most advanced fortification network in all of world history. You basically make a new Great Wall of China, except that it has huge guns and modern technology. This new fortification, the Maginot Line, really was impenetrable. It extended from the southern part of the French border all of the way up to the impassable Ardennes Forrest.

Then, the French, Belgian, and British troops moved all of their best units north to cover the exposed northern stretch of border. It would be a fool’s errand to go through these troops.

The allies had essentially blocked off a German advance before war broke out. They had an impenetrable Maginot Line, and impassable Ardennes Forrest, and a huge army sealing things off up top. Germany had no shot at pushing through Central Europe like they did 15 years earlier.

…record scratch…

Except they did, but even faster. The supposedly impassable Ardennes? The Germans blasted through it like lightning. They raced north and cut off the huge army, creating supply problems and general chaos. The hugely advanced and expensive Maginot Line? It blocked the Germans, but they raced right around it.

The most impressive defensive strategy and planning of the 20th century was defeated in a matter of days/weeks, with the defending French and Belgiums getting blown out and with the UK forced to retreat off of continental Europe.”

#5. Herman the German.

“Arminius ‘betraying’ Rome.

Arminius was a fella from Germania sent to Rome as a hostage (common in the ancient world – think Theon in GoT). Spends his early life there, joins the army, becomes a Roman citizen, granted equite class. Got sent back to Germania. Decided “fuck the Romans”, hooked up with the tribal leaders, and staged a revolt. He led an army in an ambush at the Battle of the Teutoberg Forest, which is considered one of the most influential battles in world history. After the battle, Rome never again even attempted to conquer Germania.”

#4. A divided France.

“A Jewish man serving in the French military at the turn of the 20th century was kicked out of service because he supposedly gave military secrets to the Germans. There was zero evidence to back this accusation up other than Dreyfus being Jewish. The discharge was a huge affair, the soldiers lined up on either side of him, his sword was broken and his badges were cut off. He was then exiled out of the country.

Later, a journalist found evidence that the real traitor was a general. The journalist published article after article about how Dreyfus was innocent, including a letter written by a general to the general’s girlfriend that stated how much he hated France.

France was divided, everyone had an opinion about it and a strong one at that. Actual riots erupted throughout France, several people died.

The military didn’t care and sentenced Dreyfus to North Africa. Dreyfus’ family, obviously wasnt too keen in this and begged for a re-trial, considering the evidence was pretty solid against the general and not Dreyfus. The Supreme Court agreed, annulled the first judgment and tried him again. The supporters of Dreyfus were very confident that this wrong could be fixed except…Dreyfus was convicted again of a crime he clearly didn’t commit. He was sentenced to hard labor.

TThe actual traitor is tried, but found not guilty. Still feeling hatred from those who supported Dreyfus, he shaves his mustache and skips town.

Finally the president steps in in 1906 and pardons Dreyfus of all charges. Dreyfus, being a really cool guy irl and surprisingly positive about what has happened to him, reinstates in the military, becomes a general, and fights in WW1 for the French.

I can’t over-state how much this rocked the French. A famous comic entitled “they spoke of it” shows how dramatically this divided France. Families stopped talking to each other, people were murdered. Of course, this was a big display in the anti-sometimes that had taken over Europe throughout, ya know ALL OF HISTORY. This really started the “Jews will betray your country” propaganda.

tl;dr: a Jewish man is wrongly accused of selling military secrets, is discharged, tried twice, then finally acquitted. The real traitor is exposed by his ex-lover, eventually tried but found not guilty. People had strong opinions and murdered other people because of them.”

#3. Not so stupid after all.

“Roman emperor claudius. He was the great great grand nephew of Augustus Ceasar. He was born with what modern scholars think was polio or cerebral palsey. His mother called him a monster and used him as a standard for stupidity so she gave him to his grandmother who in turn trusted him to the mule driver.

He was ostrascized by his family because of his disability. He eventually became a scholar of history and wanted to enter into public offices in order to become a politician. He was denied. His nephew emperor caligula would often mock him. A conspiracy between the preatorian guard and some senators killed caligula and the emperors family. A preatorian guard found claudius hiding and named him emperor. The senators relented and named claudius emperor if he pardoned the conspirators. He did and he became the emperor.

Turns out he was a pretty good emperor. He introduced numerous reforms in legal and public works and the empire underwent its first major expansion since augustus.

Why claudius survived, some say he masterminded the conspiracy, some say the senate spared him because they thought he was meek and disabled and easy to control. Maybe it was just luck some uninvolved preatorian found him.

Caludius survied several assination attempts only to be poisoned by his wife who then named her son nero as emperor.”

#2. A rigged game.

“The leader of the great and powerful Soviet Union deliberately aiding in the collapse of the communist government that gave him power.”

#1. A modern plot twist.

“Here’s another one I like: a misplace tweet by a politician brings down someone else’s political campaign.

In 2011, Democratic Congressman Anthony Weiner attempts to send a dick pic to a woman who has been sexting with over Twitter. However, he screws up and accidentally post it to his public feed. Weiner is forced to resign after it’s been discovered that he’s been sexting with multiple women. A few years later, while weiner is running for mayor of New York City, it’s discovered that she had sexted with women after the initial scandal. This inspires a teenage girl to bait Weiner and see if he will sext with her while she is underage. He does. This fact comes out during the 2016 presidential race and is a minor scandal, because his wife is Huma Abedin, a top aide to Democratic nominee Hillary Clinton. The FBI begins investigating Weiner for illegally communicating with a minor. In doing so, they discover hundreds of emails from Hillary Clinton on a laptop which he shared with his wife. Just a week and a half before the election, the FBI announces that they are going to reopen an investigation into Hillary Clinton’s emails based on this new evidence. This causes her poll numbers to drop and allows Donald Trump to win the election.”

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The Miwok (N California) played…

The Miwok (North California) played a game similar to soccer. Played by both sexes, girls were allowed to do anything, including kicking the ball & picking it up & running with it, while boys were only allowed to use their feet, but if a girl was holding the ball he could pick her up and […]

A Queens man, Raffi Stepanian…

A Queens man, Raffi Stepanian, has mined the cracks in the sidewalks in Midtown’s Diamond District, New York City, for bits of diamonds, rubies, platinum and gold to make a living. Over six days, he says he collected enough gold for two sales totaling $819. 00

Low Carb Diets May Actually Shorten Your Lifespan

If you’ve ever been on a diet, you’ve probably heard the term “low carb.” The Atkins, Keto, and Paleo diets all have different names but have one major thing in common: they dictate that people should avoid carbs and eat a whole lotta meat.

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A recent study, however, sheds some doubt about how healthy these low-carb diets really are. The analysis, published in The Lancet, found that people who eat a moderate amount of carbs actually live longer than those who avoid carbohydrates.

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Over 15,000 people participated in the study. Researchers found that people with the longest lifespans receive about 50-55% of their calories from carbs, while those who got 30% or less from carbs live an average of four fewer years. Interestingly, the study also found that people who receive 70% or more of their calories from carbs died one year earlier on average than the 50-55% crowd. When people avoided carbs in favor of meat, their chances of an earlier death rose, but if they shied away from carbs in favor of foods with plant-based fats and proteins, such as veggies, nuts, and beans, their life expectancy went up.

Photo Credit: Public Domain

Bottom line: eating a plant-based diet can help lower your blood pressure and the risk of diabetes and some kinds of cancer. Fad diets (like the low-carb/extra meat) may help you lose weight in the short term, but the long-term results may not be so healthy.

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This Museum Filled with ‘Retired’ Ventriloquist Dummies Is as Creepy as It Sounds

Are you looking for a vacation that’s both educational and creepy beyond belief? Then have we got a place for you! Pack up the kids, get in the family station wagon, and head to the Vent Haven Museum in Fort Mitchell, Kentucky. Why will you be creeped out? Because the museum is filled with ventriloquist dummies whose owners have died.

Photo Credit: Twitter,Chan315

Cincinnati businessman William Shakespeare Berger started collecting dummies in 1910. By the time he died in 1972, Berger’s collection numbered more than 500.

Photo Credit: Twitter,Chan315

The collection became a non-profit museum that people can now visit seasonally from May through September. Enjoy these photos…and try not to have any nightmares tonight.

Photo Credit: Twitter,Chan315

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You Won’t Believe These 5 Bizarre Japanese Game Shows

Japanese culture places a high value on things like respect and kindness…unless you’re on one of their game shows!

The game shows on Japanese TV are bizarre, hilarious, and they always end up with people being humiliated (usually with a big smile on their faces). Hey, it’s the Japanese way, who are we to judge?

Take a look at these 5 wacky shows and enjoy the videos as well. Enjoy!

1. Candy or Not Candy

I really hope this show makes it to the U.S. Contestants bite into objects that might be made of candy (yay!) or might just be a shoe or some other everyday item. Fun!

2. Escape a Fart

Yes, you read the name of this show correctly. Contestants on this show fart, which viewers can see in yellow, and they try to spread it around the room as much as possible. Okay!

3. Dotch

If you win this game show, you get to enjoy a delicious meal prepared by a chef. If you lose, you have to watch the winners eat while you starve. Good times!

4. Dero! Dero!

In this show, people must answer questions and solve puzzles. The added bonus? They do it in scary situations, like a room that’s slowly filling up with water. Yikes.

5. Kiss My Ass

The premise for this show is actually brilliant and I’m hoping it makes its way across the Pacific to our shores. Girls put their butts into plastic-shaped holes so no one can see their faces. Guys then have to inspect the butts and guess which one belongs to their girlfriend. I bet this show gets pretty ugly on a regular basis.

I don’t know about you, but now I’m tired of American television…

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